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Imiquimod topical for Human Papilloma Virus User Reviews

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.1 out of 10 from a total of 257 reviews for the treatment of Human Papilloma Virus. 61% of reviewers reported a positive experience, while 20% reported a negative experience.

Imiquimod topical rating summary

7.1/10 average rating

257 ratings from 284 user reviews.

Compare all 18 medications used in the treatment of Human Papilloma Virus.

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Reviews for Imiquimod topical

  • Anonymous
  • Taken for 1 to 6 months
  • August 10, 2019

Aldara (imiquimod) "I contracted HPV through someone... I don't know who, but I have been having my fair share of fun. I was nervous at first, but the people who I continued to see didn't care. I initially had them burned off on the shaft of my penis, but it left a scar. So when they came back, I decided to go the cream route. Luckily, places like the LGBT center provide cheap prescriptions for people who can't afford them like me (paid like $10-15 for a good supply). Anyways, I've been using Aldara for 4-5 weeks now, and it's finally working its magic. I've had it twice where it seems to open up as a sore, then scab up and heal. People definitely sweat this as the end of their sex lives or stress over it too much. It's not the end of the world... it will heal... and our bodies will go back to 'normal'. Hang in there!!!"

9 / 10
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196 Report
  • Dee...
  • Taken for less than 1 month
  • November 12, 2015

"I am female and was diagnosed with genital warts when I was 22 years old. I thought my life was over. I was prescribed Aldara cream, and my gyno told me to use just a tiny bit and to try to only put it on the warts and not the surrounding skin. I remember feeling a little soreness but nothing that I couldn't handle. I had a mild case of warts near the opening of my vagina, and they flattened after a week and were completely cleared after 2.5 weeks. I couldn't believe it! Want to know the best part? I am 33 years old, and they have never come back! Turns out my life wasn't over after all!"

10 / 10
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167 Report
  • Anonymous
  • August 6, 2020

Aldara (imiquimod) "I am happy to report that I did not experience any side effect symptoms at all except maybe some very mild sensitivity where the medicine was placed. My routine included taking a shower before bed, waiting 10 minutes to completely dry, apply a little bit of vaseline on the surrounding skin that was not affected, and rubbing a tiny amount onto the warts. In the morning, I make sure to rinse off the medication as soon as I wake up and take my daily vitamins to boost my immune systems even further. At first I was nervous nothing was happening because I didn’t feel any symptoms. After the second dose, I noticed the warts shrinking dramatically. After the third, all the small ones have disappeared and the one medium one is almost gone. Make sure you only use a small amount. My doctor said to throw away anything unused and start a new satchel every time. Anyways, I’m here to say that this medication really works and there is definitely a light at the end of the tunnel!!"

10 / 10
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91 Report

Frequently asked questions

  • M56
  • August 26, 2018

Aldara (imiquimod) "Aldara is super efficient. Here is my advice: - only apply 3 times a week, reduce if you feel too much pain. - when starting the treatment, only apply a really tiny amount of cream on each wart with the end of a cotton bud. Only when you are ready, start applying a tiny bit more, but it should stay minimal. - it will create discomfort. Use baby wipes for the toilet; buy an intimate gel to take care of the area that is infected. I took 2 showers a day during the treatment to keep the area clean at all times. No pyjama bottoms to avoid any contact. - the pain is OKAY. It can burn healthy skin in the night when the warts with cream rub against it. Put some tiny plasters opposite the wart for the night. It gets itchy during the day, but stay busy. - be positive: eat healthily, stop smoking. Have someone to help you go through it. Had 6 genital warts and 5 were completely gone by week 2. Still treating 1, but it's now barely visible. Go for it and good luck, stay positive!"

10 / 10
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  • Itwil...
  • April 7, 2020

Aldara (imiquimod) "I used Aldara for around 10 weeks. I had anal warts at the time and one on my Gooch. Aldara made my ass really red and raw and warts didn't seem to go away or change in appearance. What I did notice though was that warts went away over the next 3 months without using anything as I was travelling and didn't have any supply. Aldara is used to help boost the immune system in targeting the HPV virus (Which by the way is NOT permanent) there is so much old information out there and those of you who are just beginning your journey know that it is temporary (I know it sucks and there are so many emotions BUT you will come out the other side!). My dermatologist told me this first hand and people who are healthy will naturally clear this virus. It incubated for around 6 months and then symptoms appear. Those with Immune deficiencies will struggle to clear it, unfortunately. Cryotherapy takes the wart off and Aldara boosts the immune system to fight infection."

6 / 10
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Are you taking this medicine?

  • Anony...
  • March 21, 2019

Aldara (imiquimod) "I’ve been on the aldara for a week. My first application was okay no pain whatsoever. Note: I use small amounts overnight every alternative day on infected area on my labia. I realized that I was getting really tired the day after but that was it. After the first application it just got worse, the pain is unbearable. I can’t sleep at night because of the pain . I now have pink sores around the uninfected parts . The space between my thighs and vagina are pink and saw it also looks like eczema. But with all this pain, the cream is working wonders , in just a week 70% of my warts are gone. Just the stubborn ones are left. They are big but are getting smaller, but is it worth the pain ? I think so because I’m still continuing with it . I’m desperate for these to be gone and the cream is sure removing them . If you can’t take pain then don’t but if you’re a hardcore go getter like me, it’s worth the try . I hope this information helps someone this is my honest experience."

8 / 10
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  • Ads
  • Taken for 1 to 6 months
  • December 24, 2019

Aldara (imiquimod) "First off you're in for a pretty bad 16 weeks or longer! There's no sugar coating it. Less cream is more and more is too much, you'll notice the warts will get worse before they get better that's your body trying to fight it off. Avoid sex at all cost I say that because I couldn't resist 3 times during the treatment and I went through a lot of pain with ulcers due to the friction however sometimes you can get away with light masturbation. If you get ulcers I used lignocaine gel 2% it's a anaesthesia that just drips on. Try and clean the area twice a day and if you have ulcers just run cool-warm water over it no matter how painful it is to keep it clean so you don't get infection. If you get really bad ulcers it's ok to stop treatment for a week to heal then continue treatment I had to stop treatment 3 times due to bad ulcers. The final thing to say is don't give up it took 13 long weeks till I finally saw improvement and I'm about to hit 16 weeks and the warts are pretty almost gone."

6 / 10
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More FAQ

  • Freeeee
  • April 5, 2011

Aldara (imiquimod) "I was extremely hesitant to use this medicine because of the price and because I had read horror stories about it online. But I was desperate because of unsightly warts, so I took the plunge. I made sure to apply with a magnification mirror and a q-tip. I can't stress enough how important it was to ONLY apply it exactly where the warts were. My side effects included swelling and itching around the affected area and some fatigue/aches. After using it 4 times, my warts were gone. Worth it worth it worth it. Just be careful not to put it on any healthy skin."

10 / 10
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  • Wartson
  • Taken for less than 1 month
  • May 13, 2020

Aldara (imiquimod) "I was skeptical i even booked an appointment to get my foreskin circumcised. My warts were all around my inner foreskin so when i pulled down my foreskin they were all around that area of my penis. Dr refered to them as circumferential. They were not subtle at all as well so many i lost count. Well i got aldara. Its expensive. I got 9 sachets used 1 sachet for 2 applications (closed an open sachet with a peg). I'd apply it every 2nd day. When applying, i applied it on the warts then i'd rub into them till it disappeared. After that id apply again and left it on the warts till it dissolved by itself. I applied it from 27th of April to the 12th of May. And they started shrinking and before I knew it they were all gone. For me there was ZERO pain in the whole process. I recommend it highly. Trust me it works. And works well"

9 / 10
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  • liv
  • October 26, 2020

Aldara (imiquimod) "I got prescribed Aldara by my local sexual health clinic to treat genital warts. I thought my warts were the end of the world until I used Aldara. After applying the cream twice (as directed, only on the warts and every other night, washing it off in the morning) boy did I regret my life choices. My entire vagina swelled up the following day, and ulcer-type sores appeared EVERYWHERE in that area. I couldn’t move without being in excruciating pain and I almost passed out every time I peed. I ended up in hospital on a 7 day course of antibiotics, as well as dihydrocodiene to manage the pain. STAY AWAY FROM THIS CREAM - it should not be prescribed!!! After doing extensive reading online about Aldara, I quickly realised that so many people had been through the same as me. The warts eventually go away on their own, or there are other treatments such as freezing them off. Please please stay away from this cream."

1 / 10
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41 Report
  • Tammy
  • Taken for less than 1 month
  • March 8, 2021

Aldara (imiquimod) "This drug is magicccccc!! Now read this carefully. Do NOT apply too much! You don’t have to finish the whole sachet. I got two warts on my genital area on extremely sensitive skin. They weren’t really bothering me but I was worried about them spreading to other places. I took a q-tip and applied a very thin layer on each making sure to rub until the cream disappeared. I tried to leave it on a bit to dry completely so the discharge won’t spread it to other places of the vagina. GET RID OF THE SACHET ONCE YOU OPEN IT, don’t reuse it. My wart fell off in one day honestly I couldn’t even believe it. The cream really worked for me, hope it works for you with no crazy side effects."

10 / 10
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34 Report
  • Not...
  • November 25, 2019

"I NEVER leave reviews for anything... but this one hits a nerve. I contracted anal warts - no bloody idea how to be honest, but anyways. 7 sessions of cryo didn't help because it was too big by then. It measures about 1.5x2.5cm cluster, it was becoming painful to sit. I was shattered. Dr suggested Aldara, but even she said she wasn't confident because it is quite big. First two weeks it was very itchy, very sore didn't see much difference. Then out of no where I see parts of the wart simply falling off.. it has now reduced to about 30% of the size in 3.5 weeks. Im using it every 2 days. Keen to see what another few weeks will do. If you are in pain during this period, take pain relievers. If it is itchy, use creams or powders to assist. There other things out there to help you with the temporary side effects. The end results will reward you! I hope this information has helped another person somewhere out there.. ! Good luck! In bad times, there will eventually be good times!"

9 / 10
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43 Report
  • Doc
  • Taken for less than 1 month
  • November 22, 2015

Aldara (imiquimod) "I am a physician and I was horrified to find HPV warts near my anus a few weeks ago. There were 3 small ones in a cluster and a slightly larger pedunculated one nearby. I went to my gynecologist to discuss treatment options. We agreed on Aldara. I have been usin a small amount 3 times a week and after 2.5 week they little ones are gone and the bigger one is almost gone. I was worried about it irritating the healthy tissue surrounding the warts because it was impossible (due to the location) to only get the medication on the warts, but I have only had mild irritation alleviated by a warm bath."

10 / 10
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64 Report
  • Anonymous
  • December 8, 2014

Aldara (imiquimod) "2 weeks ago I thought my life was over with the diagnosis. My doctor let me know I am not alone and over 70% of people have human papilloma virus, its just a matter of who's body's can fight off the warts developing or not. I have been using Aldara for 2 weeks and have only minor side effects like a slight itching which not sure if just my brain thinking its bad or if it was. Apply to only the spots that need. I almost think those who complain of unreal side effects slathered this on without reading directions. The only other side effect which was odd was the first night I applied my heart rate was 100 beats per minute which was strange. Lesions have shrunk in size ten folds. I'm just super pleased. I feel bad for those who cannot afford Aldara."

10 / 10
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61 Report
  • Ordin...
  • December 11, 2019

Aldara (imiquimod) "Got HPV . I did quarterly STD checks and nothing came up. I am half circumcised. It all started with a small white head kind of thingie on internal foreskin and my doctor initially said it could be a protruded sebaceous gland. So didn’t pay much attention. After 2 months that became a small cluster about 5 mm length. Thats when my doctor said its penile wart. I was devastated and got into very low mood for days. Almost thinking about this growth all the time. I was prescribed this drug. After five applications the skin got super sore and blisters appeared with pus. Doctor said that means the cream is working. I had to stop for a week or so because of the scary reaction it had. And in addition even though the warts subsided it grew back. I started applying second round and same reaction occurred after third application. Took a break again but this time the warts magically disappeared. Such a great feeling now!!!!"

9 / 10
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34 Report
  • Paris...
  • Taken for less than 1 month
  • August 15, 2015

Aldara (imiquimod) "9/10 rating simply because like all treatments currently available it gets rid of the symptom (warts) not the illness (HPV) I had a bout of genital warts, all spaced all over my genital area (clitoris included.) After having read about the treatment, I was so scared that I did not use it for the first 2 weeks but for me liquid nitrogen was way too painful. Remember; Everybody reacts differently, don't be discouraged. I am very sensitive to pain and have gone through this with no burning sensations, absolute no side-effects aside expected sensitivity and by the first week of use I noticed a considerable difference. Dosage: 3 times/week on alternating days e.g. Monday, Wednesday, Friday for 6-10 hours at night (I left it on for 8-10)"

9 / 10
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54 Report
  • Suzie
  • January 19, 2021

Aldara (imiquimod) "I was diagnosed with vin3 last yr. The cells were becoming cancer. I have now done 2 Aldara courses of 6 weeks each and all the vin3 has totally gone and there are no dodgy cells at all. I applied it 3 times a week at night and left it on for 10 hours. Week 4 I started to get a bit sore on my vulva but nothing major and was bearable. Come week 6 no sores nothing at all but only part of the vin3 had been resolved so hospital told me to carry on with another 6 week cycle. It certainly wasn't as bad as I expected and wanted to do a review so if anyone is like I was and terrified please do try it though. Everyone reacts differently and you might have no reaction or only mild like me. The main issue for me was a continued upset stomach. My hair also snapped a lot and has become dry but the hosp said its how I have reacted. It is a form of chemo so its strong stuff. Its also fantastic as saved me having all my bits mutilated!"

10 / 10
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26 Report
  • DavidC
  • April 20, 2015

"I was diagnosed with a serious case of anal warts (hpv) and when I say serious, it was really severe! My local GUM clinic first of all gave me daktarin cream to try and loosen the warts first but this really didn't do much, I then used the Aldara 5% cream and it was truly magical! Hurt like hell almost to the point where I had trouble sleeping with the burning sensation but after 2 weeks the warts were significantly reduced and the burning had subsided. It does look like I have a few scars due to how many warts there were but all in all its a lot better! 1 year later and I'm still as smooth as I was before the diagnosis!"

10 / 10
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  • Be Pa...
  • Taken for 6 months to 1 year
  • March 6, 2017

"I never leave reviews but I wanted to for anyone else in my spot and wants sound advice. I had about 10-12 small warts above my penis (pubic hair area) and 3 on the shaft. For the "larger" warts on the shaft, I received liquid nitrogen treatment which did not work well - one returned after a month and it had no impact on the other two. I was also prescribed aldara to be used 5x weekly (M-F). Let me be clear - FOR THE FIRST 6 WEEKS IT DID ABSOLUTELY NOTHING. I was let down but continued to apply it diligently. Finally, on week 7 things started getting red and inflamed. This lasted for 2-3 weeks at which point things began healing and now look FLAWLESS. Highly recommended, but BE PATIENT."

9 / 10
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43 Report
  • Its...
  • Taken for 1 to 6 months
  • May 1, 2020

Aldara (imiquimod) "Been using Aldara for almost 4 months, started in early January. Had only 4 warts total under foreskin near penis head (Uncircumcised). 2 went away within the first 2 weeks but 2 stubborn small ones stayed for an extra 3 weeks. Never had any weird symptoms or side effects. Was feeling happy again finally But then 2 weeks after I stopped treatment they all came back. I was devastated. This time they took about 6-7 weeks to disappear. Again no side effects. Didn’t get my hopes up this time, been checking every day multiple times and now they are back again :( but this time I caught them when they were very tiny dots so 2 have disappeared after just 2 applications. Hoping the other 2 go away In the next couple days as well. This has really ruined my life... I see stories of people getting rid of them forever so I’m still hopeful. Praying this to be last time I have to use aldara and they don’t come back ever again."

9 / 10
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27 Report
  • Gano
  • Taken for less than 1 month
  • August 7, 2018

Aldara (imiquimod) "Day four of using aldara on my genital area I have over 20 genital warts (GW) scattered all over my vagina and few in the entrance of my vagina (size of a pinky fingernail) I've used aldara everyday and this is my fourth day. I started getting side effects on the third day (burning, itching, white vaginal discharge and painful urination) I have a pretty good pain thresh hold hence why I’m using it every day. I noticed today that one GW is getting smaller which was the biggest one on my left labia entrance. I hope this works and will keep you updated."

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  • Anonymous
  • February 1, 2015

Aldara (imiquimod) "I was prescribed Aldara for internal gw. When I finally found a doctor to acknowledge that they existed internally, they were bad. They almost looked like fingers. I say this to make the point that I had a serious case of them. I was put on Aldara for three times a week until 16 weeks. This was the most painful experience I have ever had in my life. I cried in pain for the first several weeks. The itching was almost unbearable in and of itself. I also got very severe ulcers around the treatment sight. I found it helpful to take an allergy pill for the itching and melatonin to help me to sleep with the pain. All that being said, after 16 weeks my gw problem was 90 percent gone.I was given another month's worth for the last remaining few."

8 / 10
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  • Lucie
  • July 1, 2020

Aldara (imiquimod) "The cream worked amazingly! My warts cleared away within 2 weeks of using the cream. The skin where the warts were is now smooth and wart free. However, it was incredibly painful- cream causes severe skin reactions. For me I developed sores and blisters on my vagina after the first week. When I peed it felt like my skin was on fire because it made contact with the blisters. I found I couldn't sit or walk without being in agony. However I persisted as and by the end of the week it was clear. Some tips ! -aloe vera is your best friend. Apply it as often as you can because it will help with the blisters and irritated skin -when peeing, take a class of cold water and pour it at the same time, or squired bottled water. This really helps with the burning and stinging. Also apply aloe vera after peeing -DONT apply to much cream or leave it on for more than 10 hours. I think lathering the cream on didn't help the severe reactions I was having"

10 / 10
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23 Report
  • Htown...
  • Taken for 1 to 6 months
  • June 16, 2017

Aldara (imiquimod) "I had a very large cluster of anal warts. I went to two colon rectal specialists. The first one was a male and insisted that the infection and removal of warts could only be treated via surgery which would have costs close to $10,000 dollars. So I got a second a opinion from a female colon rectal specialist who also felt that surgery was the best option. That being said she allowed me to try Aldara first. Let me just say that Aldara is a miracle drug! After 8 weeks of treatment and monitoring with my doctor, 100% of the warts were gone. Even my doctor was floored that Aldara was able to treat even the worst cases of anal warts. She would have had me surgery the next day if it weren't for Aldara. It's been a year with no recurrence"

10 / 10
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  • Nicki
  • Taken for less than 1 month
  • July 27, 2020

Aldara (imiquimod) "I've been using Aldara for just over 3 weeks now. I had genital and anal warts all over. They were in clusters and stuck together. But just after week 1 I could tell a difference. Now I only have a few left but you can barely see them. I'm going for a check up tomorrow but I think I might need some more just to get rid of the extra marks. However I would definitely recommend this to anyone with genital warts! It's not a quick fix but you have to be patience with it. It WILL work and if you are experiencing pain, blisters or swelling it means the cream is working as it's the cells dying to get rid of the wart. So the more pain you're in the better as bad as it sounds. I went through pain, blisters and itching in the first and second week. Not so much now as they are nearly gone."

10 / 10
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22 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Human Papilloma Virus

Symptoms and treatments