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Ampicillin and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with ampicillin.

Moderate

Ampicillin Food

Moderate Food Interaction

You may experience reduced absorption of ampicillin in the presence of food. The effectiveness of the antibiotic may be reduced. Ampicillin should be administered one hour before or two hours after meals. This will make it easier for your body to absorb the medication. Penicillin V and amoxicillin are not affected by food and may be given without regard to meals.

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Moderate

Ampicillin High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

ampicillin - sodium

Parenteral ampicillin sodium contains approximately 67 to 71 mg (2.9 to 3.1 mEq) of sodium per each gram of ampicillin activity. The combination, ampicillin-sulbactam, contains approximately 115 mg (5 mEq) of sodium per 1.5 gram of total drug. The sodium content should be considered when these products are used in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention.

References

  1. (2002) "Product Information. Omnipen (ampicillin)." Wyeth-Ayerst Laboratories
  2. (2002) "Product Information. Unasyn (ampicillin-sulbactam)." Roerig Division

Ampicillin drug interactions

There are 53 drug interactions with ampicillin.

Ampicillin disease interactions

There are 5 disease interactions with ampicillin which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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