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Doxycycline for Bacterial Infection User Reviews (Page 2)

Brand names: Vibramycin, Monodox, Oracea, Doryx, Adoxa, Doxy 100, Acticlate, Mondoxyne NL, Targadox, Okebo, LymePak, Uracil, Doxy 200, Doryx MPC, Doxy-D, Oraxyl, Doxy-Caps, Alodox, Morgidox, Adoxa Pak, Avidoxy Adoxa TT Adoxa CK …show all brand names

Doxycycline has an average rating of 4.8 out of 10 from a total of 195 reviews for the treatment of Bacterial Infection. 34% of reviewers reported a positive experience, while 50% reported a negative experience.

Reviews for Doxycycline

  • Red
  • February 7, 2015

"I have had a sinus infection for 3 years now, plus Upper respiratory infection and ear infections during the really bad times. I was cultured with Staph A. and Pseudomonas that was resistant to a lot of the antibotics except doxycycline and Augmentin but I'm allergic to penicillin so doxycycline it is. 100mg 2xday and the first few days it is hard because everything is dying and my sinuses are draining like crazy but its the only things that's working. Don't lay down for an hr after taking the pill, it did burn my throat horribly but I have not had any other side effects from it except the sun sensitivity. I think this is a small price to pay to feel better and get my life back especially since the chronic fatigue from the constant infection is severe."

10 / 10
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  • L D
  • Taken for less than 1 month
  • July 14, 2019

"I had an ear infection and was prescribed this medication doxycycline. The first day was fine but then I developed severe pressure in my head to the point where I had to switch medications. I would NOT recommend this drug and a warning to people this medication can cause high blood pressure in the brain. Terrible drug. Terrible. Hence the score of a 1 I would have rated it a zero. I know if you have nothing nice to say don't say it all but this is a warning for people that this can happen and I wouldn't want anyone to go through this."

1 / 10
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48 Report
  • Deano
  • Taken for less than 1 month
  • March 11, 2020

"Doctor prescribed doxy for sinus infection. After 3 days, I am experiencing huge headaches, stomach pain and muscle pains. Am stopping this medication now. The pain it is causing me isn’t worth taking any more."

1 / 10
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43 Report

Frequently asked questions

  • DARfr...
  • October 1, 2013

"I had terrible sinusitis. My doctor tried me on a range of medication. Nothing worked until she put me on Doxycycline ( Prednisone a nasal spray). It was fantastic! Don't recall having any side effects but you must take as directed - with food and a large glass of water, keep out of sunlight etc."

10 / 10
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  • John
  • Taken for less than 1 month
  • August 18, 2019

"My Doctor prescribed me this doxycycline antibiotic orally 100mg for MRSA after the first two antibiotics failed (some sort of penicillins). The doxycycline has managed to fade the MRSA boils but not completely eradicate the infection. The side effects are by far the worst I’ve ever experienced from any other drug I’ve taken. From dizziness, nausea and the worst of all the pressure it causes in your head. My whole 10 days on this drug has consisted of being in bed or lying on my couch with anxiety from side effects. I wouldn’t recommend this drug to my worst enemy."

3 / 10
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Are you taking this medicine?

  • goodn...
  • July 26, 2016

"Started taking doxycycline for sinus infections because of other drug allergies, such as penicillin, sulfa and Cipro. I take it between breakfast and lunch and then between lunch and supper. I set up after taking and have no problems with this drug. Thank God I have something to take and my head feels better after the first dose. Hopefully, I will not develop any allergies to this. I have taken this for three times, 10 days at a time, now over the last three years with no problems."

10 / 10
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64 Report
  • Healt...
  • Taken for less than 1 month
  • July 16, 2014

"Prescribed 100mg 2x day for 14 days for a skin infection. It is so important that you drink lots of water & do not lie down within 30min of taking this medicine to prevent ulcers in the esophagus. I followed this and had no issues whatsoever. On 7th day I had slight nausea, take with food. Also I wanted to mention I did experience chest tightness/shortness of breath for days 3-12. It stopped 24 hours after my last dose...Prilosec helped. Recommend taking a probiotic once a day to prevent any stomach issues including diarrhea. Works great for me."

8 / 10
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More FAQ

  • Col
  • Taken for less than 1 month
  • August 18, 2018

"Finished 14(!) day course awhile back for a MRSA boil. Got another bad boil weeks later (now trying Septra/Batrim). I didn’t have any notable side effects; perhaps because I reduced refined sugar intake to near zero, drank lots of water, probiotics (not at same time), got plenty of rest punctuated with some exercise. Why so many bad reviews? I guess only problems motivate a review. A vast majority of users do fine. You may feel crummy on it for a few days as your body eliminates dead bacteria. It’s ‘germ warfare’! Hope this helps."

10 / 10
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  • unarien
  • January 10, 2016

"I have been taking this medicine for a week. Took two straight away with food. Then one a day after with food. I've had no problems until today my six day. I woke late took the tablet with only a cup of coffee about 20 mins later felt unwell with slight stomach ache and felt chills all over my body. Felt bloated and sick so quickly got something to eat. And within a hour felt better do not take this on a empty stomach. Last day tomorrow. It's a good antibiotic... got rid of my upper respiratory infection and tooth infection..."

9 / 10
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  • Dukie
  • Taken for less than 1 month
  • March 24, 2019

"I have been on Doxycycline for 4 days, in conjunction with an expectorant, for a sinus infection. Script is for 10 days. I have followed "how to use this medication" received from the pharmacy, including drinking non caffeine drinks and have had no negative interaction with this medication. As a matter of fact my symptoms broke today but as with any medication even though I am feeling better I will complete the 10 day round of this antibiotic. I am allergic to penicillin and diagnosed with epilepsy and find this antibiotic one of the best I have taken and have not had any med interactions. In addition to medication rest and plenty of fluid assist in recovery."

10 / 10
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  • Maryn...
  • February 16, 2014

"I had minor surgery and developed cellulitis and was put on doxycycline. It made some immediate improvement in the pain and swelling. The culture came back as MRSA. 10 days of doxycycline was extended for 2 more weeks, but after 5 days, with infection not completely gone, I switched to vancomycin infusions for 25 days until I was considered healed. The problem wasn't the medication, rather it was the lousy suturing with internal stitches that started emerging through the wound for weeks, keeping the infection deep in my thigh. Then I got a bad cold or flu with a terrible sinus infection so I started taking the remaining doxycycline. I don't think I've taken it for sinus before, but I felt better right away and no real side effects. Great!"

8 / 10
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72 Report
  • Super
  • Taken for less than 1 month
  • January 16, 2020

"I had a bacterial infection Ureaplasma Urealyctum and was definitely hesitant to take this doxycycline pill due to the nasty reviews. The first time I took this medication it was terrible but that was because I took it on an empty stomach. It takes about 30 minutes to kick in and if you haven't eaten it will be miserable but once I ate 30 minutes prior to taking each pill, I didn't experience any nausea or vomiting."

7 / 10
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  • Axeth...
  • Taken for less than 1 month
  • February 12, 2020

"I have a bad sinus infection so I called my doc who I see weekly because my bp and they gave me this. With in 20 mins of my first does the sinus pressure became beyond extreme, I became dizzy, extremely hot sweating (it’s cold where I live) and I blared my air conditioner, and so nauseous I puked. Now after vomiting it’s still intense and had to take a migraine pill and an anti nausea pill. If you have a sinus infection stick with the Amoxicillin clav. This pill IS AWFUL"

1 / 10
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35 Report
  • Anonymous
  • July 24, 2012

"I took this medication for 4 days and had severe side effects. It started out with a stomach ache, nausea, diarrhea then I felt like I had the worst case of the flu. Body aches, chills, low grade fever, dizzy, weak, sore skin plus, the infection I was taking it for only got worse. It's been 4 days since I stopped taking and I still feel horrible."

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  • Jenna...
  • Taken for less than 1 month
  • November 29, 2016

"This antibiotic works well for me, but side effects stink. Took it for a bacterial infection. I was advised to take it on an empty stomach, but within 30 mins I get super nauseous and dizzy. Started eating a small amount of food before and after and feel less nauseous. I prepare myself to be miserable for a couple hours in the morning after taking it and then take my second dose before bed so I can sleep it off."

6 / 10
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  • very...
  • October 12, 2015

"I took two pills. the second pill seemed to have been stuck in my chest about three hours after I took it. I had heart burn like I had never ever had before. Then started nausea and vomiting for about 24 hours. Went to ER they said my esophagus was swollen and inflammed and gave me meds Two days later went to digestive doctor he said that pill is common for this. It has caused people to go through same thing. It has been almost a week, with two visits to ER and now a appointment set up to see esophagus specialist. I am finally getting better. Hopefully this night mare will be over soon. Just be cautious, this has been a bad experience for me."

1 / 10
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  • kittos
  • Taken for less than 1 month
  • March 4, 2017

"I have taken doxy before and was fine both then and now .I was taking it for a sinus and lung infection. I have no complaints as long as I stick to the instructions . ALWAYS drink A WHOLE GLASS OF WATER (250 ml's +) with the dose . avoid dairy foods and avoid anything high in metals iron, magnesium, zinc etc. DON'T lie down for at least 20 minutes after . no side affects ."

8 / 10
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  • Missy...
  • Taken for less than 1 month
  • December 2, 2016

"Been on Doxy for a severe sinus infection I got in early October. Got it on Monday, took it, felt kinda achey nothing too serious. It's now Friday. I've been out of work since Wed, migraine, throwing up, fever, chills, horrible aches and pains. I've never felt so bad on an antiobiotic. Stopping today & calling the doctor."

1 / 10
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  • krazzee...
  • Taken for less than 1 month
  • July 15, 2017

Doxy 100 (doxycycline) "This is my last day of the 10 day for sinus infection and I am taking it to a lab to get it anaylized. Something must be illegal with this drug that it is prescribed so easily without specific instructions. I have been sick all week. Sinusitis and the affects of this drug has kept me in bed most of the week. I got ill on a weekend and had to go to one of those 'clinics', Next time I will go to E.R. I lost an entire week of my life. i.e. shoulder/neck pain, sore throat, 'something in my eye",dryness, light-headed-ness, lethargic, loss of appetite, dry nose, restless sleep, yet sleep all day, nausea, feel bloated, some diarrhea, and mentally disconnected. I was not a happy camper. And now on the 10th day, I still have an infection, yellow mucous."

1 / 10
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  • Carol...
  • February 22, 2016

"Day 4 of this medication. Taking it for a sinus infection. Sinus pain and pressure are gone. I have now developed congestion in my lungs and it hurts to breath. My stomach is irritated and my mouth and gums are raw. It has become difficult to drink or eat. Taking with Mucinex as prescribed. I feel worse."

6 / 10
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49 Report
  • sinus...
  • June 3, 2023

"Well, where do I begin? I started taking tablets and had to take 2 straight away. I felt terrible pins and needles everywhere, chest tightness, felt sick, neck pain, and can't sleep. If people reckon these tablets are good think again. I'd sooner have a sinus infection and take these. If you have too of them it can be dangerous. Good luck to anyone who is taking these at the moment. I just hope I will feel better soon."

1 / 10
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10 Report
  • Alex
  • Taken for less than 1 month
  • April 17, 2020

"I didn’t think it was even working for my sinusitis because I had basically no side effects, but the infection cleared very quickly. I had just switched because a terrible Augmentin reaction, but this was a cake walk. Teeth sensitivity and a little bit of gastric pain if I didn’t take with food. Sun burns my skin and very minor headache. I’ve been taking probiotics daily, but other than that I’m very happy with the results."

9 / 10
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  • Bossp...
  • Taken for less than 1 month
  • May 25, 2018

"I was on doxycycline 100 mg, 2x daily for 7 days. I thought I was dying after 5 pills. I had been sick for over a week and the urgent care NP thought I should take this. I actually asked for amoxicillin and she refused. I had taken 3 doses and felt my heart race and dizzy. I called in to the urgent care but could not speak directly to her. The receptionist said I could stop taking it but she wasn’t convinced it was from the doxy. So I thought I’d push through. After dose 5, I left work at noon and went straight to my family doctor, I thought I was dying. I had watery diarrhea exploding from me. Ten times before noon! I was severely dizzy, I couldn’t even think about eating. I had cold sweats, and a weird headache. I felt like my brain was swelling!! My vision seemed bowed, that’s the only way I can explain it. I couldn’t see anything straight. He told me doxy is a horrible antibiotic, the side effects are too common and severe. He doesn’t prescribe."

1 / 10
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37 Report
  • Mr Dmu
  • Taken for less than 1 month
  • October 27, 2019

"Have been taking doxcycline for a week now and the side effects are really killing me such that I am feeling l have a serous infectionThe reason I was prescribed it was fir the risk of STIs - though the doctor didn't know the infection exactly. Just made assumptions when l explain how I was feeling after having unprotected sex. l feel headache, muscle pain, nausea, back pains, too much chest pain, joint pains, insomnia, and feeling generally sick. Now wondering should I continue taking or stop immediately???"

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30 Report
  • still...
  • Taken for less than 1 month
  • April 20, 2019

"Was prescribed doxycycline for a bad ear infection (I’m allergic to penicilllin), 5 days later I only felt worse. Experienced terrible nausea and dizziness, ended up in bed for the entire 5 days and saw no improvement. Had to go back for new prescription."

1 / 10
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32 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.